Improvement in Pain, Function and HRQoL ( Health Related Quality of Life) in Subacute Low Back Pain: A Controlled Clinical Trial of Exercise vs NSAIDs
DOI:
https://doi.org/10.28957/rcmfr.384Keywords:
low back pain, exercise, nonsteroidal anti-inflammatory drugs, Oswestry disability index, SF-36Abstract
Introduction. low back pain is a persistent cause of consultation and disability in patients; according to its temporal evolution, it can be classified as acute, subacute, and chronic.
Objective. To estimate the efficacy of an exercise program compared to non-steroidal anti-inflammatory drugs (NSAIDs) in patients with Subacute Low Back Pain (SLBP).
Methods. Single-blind, randomized controlled clinical trial in 90 patients with SLBP with or without radiculopathy, 46 were assigned to an exercise program and 44 to NSAID treatment. The primary outcome was improvement in pain, and the secondary outcomes were improvement in function, quality of life, work absenteeism, and depression with a 6-month follow-up.
Results. Pain did not show differences between the groups at one month 8.16 (95% CI -2.19 to 18.51). In the exercise group, it improved from 47.3 (SD: 19.8) to 28.8 (SD: 20.5), p <0.001, and in the NSAID group from 45.2 (SD: 22.6) to 34.9 (SD: 25.0), p = 0.018. Function, as measured by the Oswestry Disability Index (ODI), improved at one month in the exercise group (p<0.001). Physical function was better at one month in the exercise group (p= 0.038). The improvement in pain, function, and quality of life was maintained at 3 and 6 months in both groups. Recurrence was higher in the NSAID group: 25.5% vs. 7.1% (p= 0.04) after one month; 25.5% vs. 7.1% (p= 0.04) and 20.5% vs.5% (p= 0.04), at 3 and 6 months.
Conclusion. Supervised exercise was more effective than NSAIDs in reducing disability and recurrences and improving physical function in patients with DLS.
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