Cardiorespiratory fitness in patients with fibromyalgia: a systematic review with meta-analysis
DOI:
https://doi.org/10.28957/rcmfr.385Keywords:
Fibromyalgia, cardiovascular capacity, physical fitness, oxygen consumption, meta-analysisAbstract
Introduction. Fibromyalgia is a chronic disease characterized by widespread musculoskeletal pain that can lead to deterioration in cardiorespiratory capacity; however, to date it is not clear what the cardiorespiratory compromise is in patients with this condition.
Objectives. To determine the cardiorespiratory capacity of patients with fibromyalgia and analyze the differences with healthy controls.
Methods: A systematic search was performed in PubMed, Web of Science, ScienceDirect, Redalyc, Scopus, Lilacs and Google Scholar databases. Observational studies published in English, Spanish and Portuguese that assessed the cardiorespiratory capacity in patients with fibromyalgia compared with healthy subjects were included. The methodological quality was assessed using the Newcastle-Ottawa scale. Under a random-effects model, the pooled effect size was calculated with the standardized mean difference and its 95% confidence interval; heterogeneity was analyzed using the I-square (I 2) test. Subgroup analyses were performed to assess the influence of the type of clinical exercise testing used.
Results. 14 studies, with a total of 1623 participants (all women), that met the inclusion criteria were included. A significant difference in distance covered on the six-minute walk test was found in women with fibromyalgia compared with healthy women. the studies with ergospirometry showed inconclusive results.
Conclusions. Patients with fibromyalgia have lower cardiorespiratory capacity on the six-minute walk test compared to healthy controls. In this sense, research is needed to establish adequate methods of measuring cardiorespiratory fitness that take into account the particular conditions of the patients with this disease.
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