Effectiveness of exercise and vitamin D3 on muscle mass and strength in rheumatoid arthritis
DOI:
https://doi.org/10.28957/rcmfr.386Keywords:
Rheumatoid arthritis, physical exercise, vitamin D3, exercise therapy, VenezuelaAbstract
Introduction. Rheumatoid arthritis is an autoimmune disease with a chronic inflammatory process of the joints and an increased catabolic response that predisposes to a high loss of muscle mass.
Objective. To evaluate the effectiveness of a resistance exercise program plus supplementation with vitamin D3 on the mobility, and the muscle mass and strength of patients with rheumatoid arthritis who attend the consultation of physical medicine and rehabilitation.
Methods. Randomized controlled clinical trial conducted in 30 patients equitably distributed into three groups: control group, group with exercises for 10 weeks and a group with exercises for 10 weeks plus supplementation with 2,000 IU of vitamin D3. The variables were evaluated at the beginning of the study and 10 weeks after the start of the intervention.
Results. The mean age of the participants was 57.73 years and the vast majority of them (93.3%) were women. In the first item of the evaluation in the SPPB scale (balance test) an initial average of 3.5 and a final average of 3.7 was observed, in the second item (gait speed test) the initial average was 2.8 and the second was 3.3, and in the third item (standing up from a chair) the initial average was 1.1, and the final was 1.6, with a significant final result between them (p<0.001). The measurement of the mass using ultrasound evidenced a significant value in the group of exercises plus supplementation with vitamin D3.
Conclusion. The intervention during 10 weeks of strength exercises plus supplementation with vitamin D3 (2,000 IU) produces an improvement in the items of the SPPB scale and in the muscle mass of the biceps brachii and rectus femoris, which might have an impact on the reduction of the risk of falls in patients with rheumatoid arthritis.
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