Infiltración del tronco encefálico en enfermedades hemato-oncológicas avanzadas; manifestaciones clínicas y orientación diagnostica
DOI:
https://doi.org/10.28957/rcmfr.v28n2a6Palabras clave:
Neurolinfomatosis, tronco encefálico, nervios craneales, electrodiagnóstico, diagnóstico por imagen.Resumen
El compromiso de los nervios craneales secundario a progresión de enfermedades oncológicas al tronco encefálico es una entidad infrecuente con alto riesgo de pérdida funcional, su presentación clínica varía de acuerdo con la naturaleza del diagnóstico y la estructura afectada.Dentro de las enfermedades con mayor riesgo de progresión al tronco encefálico se encuentran las malignidades hematológicas que pueden infiltrar los núcleos de los nervios craneales de forma directa, proceso denominado neurolinfomatosis. El propósito de este artículo es describir las manifestaciones clínicas del compromiso de los nervios craneales en el tronco encefálico secundario a infiltración, mediante la presentación de casos clínicos y una breve revisión de la literatura con el fin de brindar elementos que faciliten la orientación de las intervenciones diagnósticas y terapéuticas por parte del servicio de Rehabilitación.
Referencias bibliográficas
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2. Jiménez Zapata HD, Rojas Medina LM, Carrasco Moro R, Martínez Rodrigo A, García-Cosio Piqueras M. Cauda equina syndrome secondary to neurolymphomatosis: Case report and literature review. Neurocirugia [Internet]. 2017;29(3):138-42. Available from: http://dx.doi.org/10.1016/
j.neucir.2017.07.001
3. Baehring JM, Damek D, Martin EC, Betensky RA, Hochberg FH. Neurolymphomatosis 1. Neuro Oncol. 2003;(April):104-15. http://dx.doi.org/10.1093/neuonc/nop021
4. Grisariu S, Avni B, Batchelor TT, Bent MJ Van Den, Bokstein F, Schiff D, et al. Neurolymphomatosis.: an International Primary CNS Lymphoma Collaborative Group report. 2016;115(24):5005-12. http: //dx.doi.org/10.1182/blood-2009-12-258210
5. Tomita M, Koike H, Kawagashira Y, Iijima M, Adachi H, Taguchi J, et al. Clinicopathological features of neuropathy associated with lymphoma. Brain. 2013;136(8):2563-78. http://dx.doi.org/10.1093/brain/awt193
6. Palma JA, Fernandez-Torron R, Esteve-Belloch P, Fontes-Villalba A, Hernandez A, Fernandez-Hidalgo O, et al. Leptomeningeal carcinomatosis: Prognostic value of clinical, cerebrospinal fluid, and neuroimaging features. Clin Neurol Neurosurg [Internet]. 2013;115(1):19-25. http://dx.doi.org/
10.1016/j.clineuro.2012.03.048
7. Odabasi Z, Parrott JH, Reddy VVB, Oh SJ. Neurolymphomatosis associated with muscle and cerebral involvement caused by natural killer cell lymphoma: A case report and review of literature. J Peripher Nerv Syst. 2001;6(4):197-203. https://doi.org/10.1046/j.1529-8027.2001.01018.x
8. Sakai N, Ito-Yamashita T, Takahashi G, Baba S, Koizumi S, Yamasaki T, et al. Primary neurolymphomatosis of the lower cranial nerves presenting as Dysphagia and hoarseness: a case report. J Neurol Surg Rep
[Internet]. 2014;75(1):e62-6. http://dx.doi.org/10.1055/s-0033-1363505
9. Finsterer J, Grisold W. Disorders of the lower cranial nerves. J Neurosci Rural Pract [Internet]. 2015;6(3):377. http://dx.doi.org/10.4103/0976-3147.158768
10. Toledano M, Siddiqui MA, Thompson CA, Garza I, Pittock SJ. Teaching NeuroImages: Diagnostic utility of FDG-PET in neurolymphomatosis.
Neurology. 2013;81(1):2013.http://dx.doi.org/10.1212/WNL.0b013e
318297eef5
11. Kimura J. Facts, fallacies, and fancies of nerve conduction studies: Twenty-first annual Edward H. Lambert lecture. Muscle and Nerve. 1997;20(7):777-87. http://dx. d o i . o rg/10 .1002/(SICI)1097-4598
(199707)20:73.0.CO;2-4
12. Leandri M. Trigeminal evoked potentials in cluster headache. 2000;43-6
13. Kimura J. The Blink Reflex. In: Electrodiagnosis in diseases of nerve and muscle: principles and practice. 2nd ed. Philadelphia: Oxford University; 1989. p. 307-31.
14. Morelli N, Mancuso M, Frittelli C, Falorni M, Gallerini S, Paolo DS, et al. Multiple cranial nerve palsies in testicular lymphoma: Report of a case. Neurologist [Internet].2007;13(4):222-4.
15. Mauermann ML. Neurologic Complications of Lymphoma, Leukemia, and Paraproteinemias. Contin Lifelong Learn Neurol [Internet]. 2017;23(3):669-90. http://dx.doi.org/10.1212/CON.0000000000000468
Cómo citar
1.
Rivera AH, Barrera Castro SM. Infiltración del tronco encefálico en enfermedades hemato-oncológicas avanzadas; manifestaciones clínicas y orientación diagnostica. Rev. Colomb. Med. Fis. Rehabil. [Internet]. 2 de abril de 2019 [citado 19 de abril de 2024];28(2):126-32. Disponible en: https://revistacmfr.org/index.php/rcmfr/article/view/221
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Publicado
2019-04-02
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Casos clínicos
